Получение эффективных лекарственных форм методом хроматографического разделения оптических изомеров

Authors

  • Е.Н. Решетова Институт технической химии УрО РАН

DOI:

Keywords:

Abstract

Author Biography

  • Е.Н. Решетова, Институт технической химии УрО РАН
    кандидат химических наук, младший научный сотрудник

References

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  2. Колтунов К.Ю. Энантиоселективный синтез органических соединений: учеб. пособие. – Новосибирск, 2010. – 41 с.
  3. Решетова Е.Н., Аснин Л.Д. Закономерности хроматографического разделения энантиомеров профенов на эремомицинсодержащей неподвижной фазе // Всерос. симпозиум «Хроматография и хромато-масс-спектрометрия». – М., Клязьма. – 2008. – C. 100.
  4. Решетова Е.Н., Аснин Л.Д. Термодинамика адсорбции энантиомеров напроксена на химически модифицированной целлюлозе в условиях ВЭЖХ // ХI Молодежная конф. по органической химии. – Екатеринбург, 2008. – С. 92.
  5. Энгельгардт Х. Жидкостная хроматография при высоких давлениях. – М.: Мир, 1980. – 245 с.
  6. Berthod A., He B.L., Beesley T.E. Temperature and enantioseparation by macrocyclic glycopeptide chiral stationary phases // J. Chromatogr. A. – 2004. – Vol. 1060. – P. 205–214.
  7. Cox G.B. Packing materials for enantioselective preparative. chromatography // Analusis Mag. – 1998. – Vol. 26. – № 7. – P. M70–M76.
  8. Cyclodextrin chiral stationary phases for liquid chromatographic separations of drug stereoisomers / A. Berthod [et al.] // J. Pharm.& Biomed. Anal. – 1990. – Vol. 8. – № 2. – P. 123–130.
  9. Enantioselective chromatography in drug discovery / Y. Zhang [et al.] // Drug Discov. Today. – 2005. – Vol. 10. – № 8. – P. 571–577.
  10. Enantioseparation of R, S-ibuprofen using Simulated Moving Bed (SMB) chromatography / J.H. Won [et al.] // Hwahak Konghak. – 2001. – Vol. 39. – № 6. – P. 685–691.
  11. Federsel H.-J. Facing chirality in the 21st century: approaching the challenges in the pharmaceutical industry // Chirality. – 2003. – Vol. 15. – № S1. – P. S128–S142.
  12. Gyllenhaal O., Stefansson M. Reversal of elution order for profen acid enantiomers in normal phase LC on Chiralpak AD // J. Pharm. Biomed. Anal. – 2008. – Vol. 46. – № 5. – P. 860–863.
  13. Gyoung Won Kang, Joung Ho Ko, Won Jo Cheong. Thermodynamic study of enantioseparation of arylpropionic acids with a chiralcel OJ-H stationary phase // Journal of Liquid Chromatography & Related Technologies. – 2005. – Vol. 28. – № 4. – P. 513–526.
  14. Lien Ai Nguyen, Hua He, Chuong Pham-Huy. Chiral Drugs. An Overview // International Journal of Biomedical science. – 2006. – Vol. 2. – № 2. – P. 85–100.
  15. Miller L., Bergeron R. Analytical and preparative resolution of enantiomers of verapamil and norverapamil using a cellulose-based chiral stationary phase in the reversed-phas // J. Chromatogr. – 1993. – Vol. 648. – № 2. – P. 381–388.
  16. Mullangi R., Yao M., Srinivas N.R. Resolution of enantiomers of ketoprofen by HPLC: a review // Biomed. Chromatogr. – 2003. – Vol. 17. – № 7. – P. 423–434.
  17. p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells / A. Janssen [et al.] // Biochem. Biophys. Research Commun. – 2008. – Vol. 365. – № 4. – P. 698–703.
  18. Separation of ibuprofen enantiomers by supercritical fluid simulated moving bed chromatography / S. Peper [et al.] // Sep. Sci. Technology. – 2002. – Vol. 37. – № 11. – P. 2545–2566.
  19. Spectrophotometric and polarimetric detectors in liquid chromatography for the determination of enantiomer ratios in complex mixtures / W. Boehme [et al.] // Anal. Chem. – 1982. – Vol. 54. – № 4. – P.709–711.
  20. Todd P.A., Clissold S.P. Naproxen: a reappraisal of its pharmacology, and therapeutic use in rheumatic diseases and pain states // Drugs. – 1990. – Vol. 40. – P. 91–137.
  21. Welch C.J. Evolution of chiral stationary phase design in the Pirkle laboratories // J. Chromatogr. A. – 1994. – Vol. 666. – № 1–2. – P. 3–26.

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  1. Asnin L.D. Hromatografia - na blago Rossii. - M.: Granica, 2007. - S. 34-42.
  2. Koltunov K.U. Enantioselektivnyj sintez organiceskih soedinenij: uceb. posobie. - Novosibirsk, 2010. - 41 s.
  3. Resetova E.N., Asnin L.D. Zakonomernosti hromatograficeskogo razdelenia enantiomerov profenov na eremomicinsoderzasej nepodviznoj faze // Vseros. simpozium <>. - M., Klaz’ma. - 2008. - C. 100.
  4. Resetova E.N., Asnin L.D. Termodinamika adsorbcii enantiomerov naproksena na himiceski modificirovannoj celluloze v usloviah VEZH // HI Molodeznaa konf. po organiceskoj himii. - Ekaterinburg, 2008. - S. 92.
  5. Engel’gardt H. Zidkostnaa hromatografia pri vysokih davleniah. - M.: Mir, 1980. - 245 s.
  6. Berthod A., He B.L., Beesley T.E. Temperature and enantioseparation by macrocyclic glycopeptide chiral stationary phases // J. Chromatogr. A. - 2004. - Vol. 1060. - P. 205-214.
  7. Cox G.B. Packing materials for enantioselective preparative. chromatography // Analusis Mag. - 1998. - Vol. 26. - No 7. - P. M70-M76.
  8. Cyclodextrin chiral stationary phases for liquid chromatographic separations of drug stereoisomers / A. Berthod [et al.] // J. Pharm.& Biomed. Anal. - 1990. - Vol. 8. - No 2. - P. 123-130.
  9. Enantioselective chromatography in drug discovery / Y. Zhang [et al.] // Drug Discov. Today. - 2005. - Vol. 10. - No 8. - P. 571-577.
  10. Enantioseparation of R, S-ibuprofen using Simulated Moving Bed (SMB) chromatography / J.H. Won [et al.] // Hwahak Konghak. - 2001. - Vol. 39. - No 6. - P. 685-691.
  11. Federsel H.-J. Facing chirality in the 21st century: approaching the challenges in the pharmaceutical industry // Chirality. - 2003. - Vol. 15. - No S1. - P. S128-S142.
  12. Gyllenhaal O., Stefansson M. Reversal of elution order for profen acid enantiomers in normal phase LC on Chiralpak AD // J. Pharm. Biomed. Anal. - 2008. - Vol. 46. - No 5. - P. 860-863.
  13. Gyoung Won Kang, Joung Ho Ko, Won Jo Cheong. Thermodynamic study of enantioseparation of arylpropionic acids with a chiralcel OJ-H stationary phase // Journal of Liquid Chromatography & Related Technologies. - 2005. - Vol. 28. - No 4. - P. 513-526.
  14. Lien Ai Nguyen, Hua He, Chuong Pham-Huy. Chiral Drugs. An Overview // International Journal of Biomedical science. - 2006. - Vol. 2. - No 2. - P. 85-100.
  15. Miller L., Bergeron R. Analytical and preparative resolution of enantiomers of verapamil and norverapamil using a cellulose-based chiral stationary phase in the reversed-phas // J. Chromatogr. - 1993. - Vol. 648. - No 2. - P. 381-388.
  16. Mullangi R., Yao M., Srinivas N.R. Resolution of enantiomers of ketoprofen by HPLC: a review // Biomed. Chromatogr. - 2003. - Vol. 17. - No 7. - P. 423-434.
  17. p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells / A. Janssen [et al.] // Biochem. Biophys. Research Commun. - 2008. - Vol. 365. - No 4. - P. 698-703.
  18. Separation of ibuprofen enantiomers by supercritical fluid simulated moving bed chromatography / S. Peper [et al.] // Sep. Sci. Technology. - 2002. - Vol. 37. - No 11. - P. 2545-2566.
  19. Spectrophotometric and polarimetric detectors in liquid chromatography for the determination of enantiomer ratios in complex mixtures / W. Boehme [et al.] // Anal. Chem. - 1982. - Vol. 54. - No 4. - P.709-711.
  20. Todd P.A., Clissold S.P. Naproxen: a reappraisal of its pharmacology, and therapeutic use in rheumatic diseases and pain states // Drugs. - 1990. - Vol. 40. - P. 91-137.
  21. Welch C.J. Evolution of chiral stationary phase design in the Pirkle laboratories // J. Chromatogr. A. - 1994. - Vol. 666. - No 1-2. - P. 3-26.

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Published

2012-12-05

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Section

Research: theory and experiment

How to Cite

Решетова, Е. (2012). Получение эффективных лекарственных форм методом хроматографического разделения оптических изомеров. Perm Federal Research Centre Journal, 4, 25-34. https://journal-dev.icmm.ru/index.php/pscj/article/view/PSCJ2011n4p4